SUVN-502 mesylate hydrate
CAS No. 1791396-45-6
SUVN-502 mesylate hydrate ( SUVN502 )
Catalog No. M12697 CAS No. 1791396-45-6
SUVN-502 (SUVN502)is apotent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSUVN-502 mesylate hydrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionSUVN-502 (SUVN502)is apotent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM.
-
DescriptionSUVN-502 (SUVN502)is apotent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM; shows high selectivity over 5-HT2A receptor and other 100 target sites; produces synergistic effects in extracellular levels of acetylcholine in the ventral hippocampus combined with donepezil and memantine; shows potential for treatment of Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
-
SynonymsSUVN502
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
Recptor5-HT Receptor
-
Research AreaNeurological Disease
-
IndicationAlzheimer Disease
Chemical Information
-
CAS Number1791396-45-6
-
Formula Weight688.62
-
Molecular FormulaC23H34BrN3O10S3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN1CCN(CC1)CC2=CN(C3=C2C=C(C=C3)OC)S(=O)(=O)C4=CC=CC=C4Br.CS(=O)(=O)O.CS(=O)(=O)O.O
-
Chemical Name1-((2-bromophenyl)sulfonyl)-5-methoxy-3-((4-methylpiperazin-1-yl)methyl)-1H-indole dimethanesulfonate hydrate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Nirogi R, et al. J Med Chem. 2017 Mar 9;60(5):1843-1859.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
2. Nirogi R, et al. J Pharm Biomed Anal. 2017 Apr 14;145:423-430.
molnova catalog
related products
-
Pimethixene
Pimethixene is a highly potent 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively).
-
5-HT1A modulator 2 h...
5-HT1A modulator 2 hydrochloride is a modulator of 5-HT1A showing an affinity of 53 nM for 5-HT1A binding.
-
Ro 60-0175 fumarate
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.